Viscosity of Contrast Media Perturbs Renal Hemodynamics
نویسندگان
چکیده
منابع مشابه
Viscosity of contrast media perturbs renal hemodynamics.
Contrast-induced nephropathy is a common cause of acute renal failure, and the mechanisms underlying this injury are not completely understood. We sought to determine how physicochemical properties of contrast media may contribute to kidney damage in rats. We administered contrast media of equivalent iodine concentrations but differing physiocochemical properties: the high-osmolality iopromide ...
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BACKGROUND N-acetylcysteine (NAC) has been proposed to prevent radiocontrast nephropathy in high-risk patients. METHODS The effect of single-dose and prolonged administration of NAC before application of either the ionic, high-osmolar radiocontrast agent diatrizoate sodium (DTZ) or the nonionic, low-osmolar radiocontrast agent iohexol (IOH) in a rat model combining uninephrectomy, salt deplet...
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Over a 12-month period four patients developed acute renal failure after undergoing radiological investigations using contrast media. Though the incidence of serious complications is low, the possibility of adverse side effects must be weighed against the usefulness of the information provided by these techniques.
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B eginning the renal physiology section with a detailed consideration of renal microvascular dynamics allows a smooth transition from cardiovascular-related topics to kidney-related topics. In addition, reductions in renal blood flow (RBF) and glomerular filtration rate (GFR) are often associated with many pathophysiological conditions including hypertension, renal failure, heart failure, and d...
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BACKGROUND Intra-arterial administration of radiographic contrast media (CM) is discussed to impair renal perfusion. The pathogenesis of contrast-induced Nephropathy (CIN) is still not clarified. OBJECTIVE This trial was performed to prove the effects of two CM with different molecular structure on renal perfusion. METHODS A prospective, randomized study on 16 pigs was designed to compare t...
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ژورنال
عنوان ژورنال: Journal of the American Society of Nephrology
سال: 2007
ISSN: 1046-6673,1533-3450
DOI: 10.1681/asn.2006111216